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Brand : Differin Generic
Composition : ADAPALENE (a-DAP-a-leen)
Differin Generic Adapalene, Differin Gel contains 0.1% Adapalene [in each gram], which is a third generation retinoid – a class of chemical compounds that are related to Vitamin A – used in the treatment of Acne Vulgaris. The exact method in which Adapalene works is not known, but retinoids are used in the treatment of various dermatological conditions because of their capacity to regulate cell growth, cellular differentiation, keratinization and inflammatory processes. In very moderate doses, Adapalene has been found to be beneficial in the treatment of Acne, besides Keratosis Pilaris [which is similar to acne] and other skin conditions.
The FDA approved usage of Adapalene for treating acne in 1996.
We sell generic medicine. generics are brand equivalent drugs which contain the same active ingredients. Generic drugs may differ in appearance, color, packaging, shape, size.
Differin gel is used in the treatment of the scourge of millions of youngsters – Acne, which appears on the skin as whiteheads, blackheads and pimples, which are very painful to the touch at times. In some people acne is present in the form of cysts. Acne is not caused by dirt housing itself in the skin, but by over-zealous sebaceous glands that produce excess oil, which stimulates bacteria to gain strength and cause inflammation of the surrounding tissues. Though this often happens during puberty when androgens – “male” hormones become active in boys and girls, the much-dreaded acne also attacks older adults. Though it occurs commonly on the face, some people find that their neck, shoulders, back, chest and legs also bear the tell-tale signs of acne.
When Adapalene Cream is applied to the skin, it gets deep inside pores that have been clogged by the accumulation of oil and bacteria, and clears this accumulation. It also prevents the formation of fresh acne.
Adapalene is also used to treat Keratosis Pilaris, which is often misdiagnosed as acne. Keratosis Pilaris manifests itself in the appearance of rough bumps on the upper arms, thighs, buttocks and other parts of the body because of an excess production of a protein called Keratin, that accumulates inside hair follicles to form numerous tiny red bumps on the skin surface, making it appear like acne.
Differin [Adapalene] is usually applied once a day, before retiring.
Before applying Differin Gel or Differin Cream, clean your face with a cleansing lotion, applied gently on the skin, removing it with a wet pad of cotton or a soft cloth. Wash your face, pat it dry, then apply a thin film of the gel on to the affected parts, carefully avoiding contact with the eyes, lips nose and mucous membranes, as well as any cuts, sunburned or eczematous skin.
Some Differin side-effects that are likely to occur during the first few weeks of administrating Differin medicine, and have been commonly reported include:-
You should stop using Differin and contact your doctor immediately if any of these common symptoms become severe, or persist, or any other unusual symptoms occur.
Better or quicker results will not be obtained if you apply excessive amounts of Differin [Adapalene] gel. On the contrary, Differin overdose may make your skin red, maybe peel off and cause you a good deal of discomfort. If ingested by mistake, call the emergency room and ask for help. US residents can call the US national poison hotline at 1-800-222-1222.
Differin Gel or Differin Cream should be stored at a room temperature of 20oC-25oC. Keep out of reach of children and pets. Discard it when it becomes outdated.
Differin Adapalene gel can irritate the skin, so any soaps or cosmetics – which are medicated or have an abrasive quality because of their high concentrations of alcohol / astringents / lime / spices –should be used with caution.
There are a number of drugs that can lead to acne or the formation of blemishes in some patients, such as anticonvulsants, corticosteroids, Disulfuram/Antabuse, Immuran [an immunosuppressant] and some thyroid medicines.
Since Differin overuse can cause irritation, check with the doctor if you have forgotten an application.
Inform the dermatologist about the ailments you have suffered / are suffering from, all the medications [prescription and OTC] you are taking including vitamins-minerals-herbal products, and particularly any allergies you have, so that the doctor can decide what medicines you should avoid while using Adapalene, and also the frequency of usage.
If your skin reacts sensitively or gets irritated while using Differin [Adapalene], you must stop using the gel at once.
Over-exposure to extreme wind or cold weather, sunlight or sunlamps will produce the same results. Usage of sunscreens and protective clothing is recommended.
Do not apply this gel to abrasions, sunburned or eczematous skin.
Never squeeze or pick at your pimples, as it will cause infection, inflammation and scarring of the area.
Those who are using Differin gel may experience dryness, scaling, burning, erythema or itching during the initial course of therapy [maybe the first 2 or 4 weeks even], but these symptoms have been found to decrease with continued use of the gel. If the reactions are severe, speak to your doctor immediately.
Pregnant women or nursing mothers should use Differin medication only if the doctor allows.
The safety of using this gel by children below 12 has not been established.
Try not to wash your face or other affected parts more than twice in a day, for it can either make healthy skin to become dry, irritate your acne-prone areas and cause a further breakout of acne. Taking a shower after exercise is required to dispel heat and moisture from your body, so that bacteria do not get a chance to multiply. Use gentle scrubs – be kind to your skin.
Avoid taking a diet which is very rich in Vitamin A, as it can be toxic.
Avoid synthetic garments and those made of lycra, as they can trap heat and moisture against your skin, and encourage growth of bacteria.
Treatment with Differin Adapalene 0.1% gel may cause dryness of the skin, erythema, burning sensation, or pruritus [itching]. If you are using other products which irritate the skin along-with Differin, it can increase skin irritation.
Chocolate lovers and those who can’t do without their French fries or other fried food, can relax – Acne does not happen because of what you’ve eaten; though a balanced diet would be more beneficial to your health.
Stress is not a direct contributor to acne either, but a good sleep and relaxation can reduce fluctuations of your hormones, that will curb production of more oil so pores will not get clogged.
Along-with Adapalene, lesser make-up for girls is recommended particularly as application of creams means more oil, which includes avoiding “sweet” scented face creams/ eye shadows / face powder / blush since it contains mica which cause irritation and / or clogging in the skin.
For boys having acne and using Adapalene, it would help to lather well before shaving. Using thinner, filmy shaving creams will help the razor to glide easily over the skin. Single-blade shaving is recommended since this works only on top of the skin, and will not cause inflammation; it will also help men if they shave down as it can reduce irritation and cuts, as well.
Using low amounts of benzoyl peroxide or sulfur will help to draw away excess oil from the skin.
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